Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.36 |
| ▸ | PRKCG | P05129 | 3/20 | 0.36 |
| ▸ | PRKCB | P05771 | 3/20 | 0.36 |
| ▸ | PRKCA | P17252 | 3/20 | 0.36 |
| ▸ | PRKCH | P24723 | 3/20 | 0.36 |
| ▸ | PRKCI | P41743 | 3/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25541010 | 0.79 | SSTR4 (0.46) | SSTR4CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL22794684 | 0.76 | LMNA (0.46) | SSTR4CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL25529096 | 0.75 | LMNA (0.49) | SSTR4CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL12691833 | 0.75 | EGFR (0.42) | EGFRCYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL1691498 | 0.73 | LMNA (0.53) | SSTR4CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL16240697 | 0.70 | LMNA (0.55) | SSTR4CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL16110169 | 0.70 | KDM4E (0.55) | SSTR4CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL18099784 | 0.70 | EGFR (0.47) | EGFRCYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL19860425 | 0.70 | TNF (0.42) | SSTR4CYP3A4CYP2D6LMNAKDM4E | |
| SCHEMBL21895689 | 0.69 | SSTR4 (0.37) | SSTR4CYP3A4CYP2D6LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | EGFR 1941/4885SSTR4 300/4885CYP3A4 4104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.