Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.42 |
| ▸ | PRKCG | P05129 | 3/20 | 0.42 |
| ▸ | PRKCB | P05771 | 3/20 | 0.42 |
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | PRKCH | P24723 | 3/20 | 0.42 |
| ▸ | PRKCI | P41743 | 3/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22794684 | 0.91 | LMNA (0.46) | SSTR4LMNACYP3A4CYP2D6KDM4E | |
| SCHEMBL25529096 | 0.87 | LMNA (0.49) | SSTR4LMNACYP3A4CYP2D6KDM4E | |
| SCHEMBL21165459 | 0.82 | SSTR4 (0.43) | SSTR4CYP3A4CYP2D6KDM4ECYP1A2 | |
| SCHEMBL19256234 | 0.81 | IMPDH2 (0.36) | SSTR4LMNACYP3A4CYP2D6KDM4E | |
| SCHEMBL1691498 | 0.81 | LMNA (0.53) | SSTR4LMNACYP3A4CYP2D6KDM4E | |
| SCHEMBL19257091 | 0.80 | IMPDH2 (0.47) | LMNACYP3A4CYP2D6KDM4ECYP1A2 | |
| SCHEMBL2126064 | 0.79 | CYP2A6 (0.40) | LMNACYP2D6KDM4ECYP1A2CYP2C19 | |
| SCHEMBL25857904 | 0.79 | EGFR (0.41) | SSTR4LMNACYP3A4CYP2D6KDM4E | |
| SCHEMBL16110169 | 0.78 | KDM4E (0.55) | SSTR4LMNACYP3A4CYP2D6KDM4E | |
| SCHEMBL16240697 | 0.78 | LMNA (0.55) | SSTR4LMNACYP3A4CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | US | disclosed |
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | SSTR4 2812/4885LMNA 1845/4885CYP3A4 1831/4885 |
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | SSTR4 2673/4885LMNA 1308/4885CYP3A4 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.