SCHEMBL25857968

SCHEMBL25857968

Cc1ccc2c(sc3c(C(F)(F)F)c(C)ccc32)c1C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.32
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25858048 0.91 HDAC3 (0.33)
SCHEMBL25857975 0.86
SCHEMBL25858049 0.85
SCHEMBL25858047 0.82 BCL2L1 (0.36) KDM4EMAPT
SCHEMBL14423252 0.79 CYP1A2 (0.35)
SCHEMBL12154091 0.75 CYP1A2 (0.33)
SCHEMBL4921456 0.74 NOTUM (0.45) CHRNA7
SCHEMBL4924769 0.74 GPR35 (0.31)
SCHEMBL4911294 0.74 NOTUM (0.41)
SCHEMBL25871161 0.74 HSD17B1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed