Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373403 | 1.00 | TP53 (0.50) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL16371578 | 0.83 | TP53 (0.47) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL1071628 | 0.83 | TP53 (0.42) | TP53LMNAHTTIDO1MAPK1 | |
| SCHEMBL20131003 | 0.81 | TP53 (0.53) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL7460990 | 0.81 | TP53 (0.48) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL4069342 | 0.81 | TP53 (0.48) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL7456749 | 0.81 | TP53 (0.48) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL7460986 | 0.77 | ADRA2C (0.51) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL6212874 | 0.77 | ADRA2C (0.51) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL29481560 | 0.77 | ADRA2C (0.51) | TP53LMNAHTTIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131969-A1 | IMPROVED PROCESS FOR THE PREPARATION OF LULICONAZOLE | KIMIA BIOSCIENCES LIMITED (IN) | 2023-07-13 | — | — | WO | disclosed |
| CN-103044192-A | Method for synthesizing luliconazole intermediate-(S)-2,4-dichloro-1-(1,2-dichloroethyl) benzene | ASTATECH CHENGDU PHARMACEUTICAL CO LTD | 2013-04-17 | — | — | CN | disclosed |