Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31468730 | 0.85 | TAAR1 (0.65) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL5299284 | 0.85 | TAAR1 (0.65) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL5294687 | 0.81 | TAAR1 (0.70) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL1042326 | 0.81 | KMT2A (0.66) | ALDH1A1KDM4ETSHRGPR55TP53 | |
| SCHEMBL25188324 | 0.79 | TAAR1 (0.72) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL715096 | 0.79 | TAAR1 (0.72) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL30434262 | 0.79 | TAAR1 (0.72) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL30503037 | 0.79 | TAAR1 (0.72) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL29350327 | 0.79 | TAAR1 (0.72) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL896903 | 0.79 | TAAR1 (0.72) | TAAR1SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227420-A1 | PRODRUGS OF MDMA, MDA, AND DERIVATIVES THEREOF | EMPATHBIO, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227420-A1 | PRODRUGS OF MDMA, MDA, AND DERIVATIVES THEREOF | COMT, PNMT, ABCB1 | TAAR1 120/4885SLC6A2 41/4885SLC6A4 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.