Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.35 |
| ▸ | IL1B | P01584 | 2/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25859445 | 0.91 | NLRP3 (0.35) | NLRP3IL1B | |
| SCHEMBL25859845 | 0.87 | NLRP3 (0.36) | NLRP3IL1B | |
| SCHEMBL31314107 | 0.84 | NLRP3 (0.34) | NLRP3FASN | |
| SCHEMBL25857850 | 0.81 | NLRP3 (0.42) | NLRP3IL1B | |
| SCHEMBL25856431 | 0.80 | NLRP3 (0.61) | NLRP3IL1B | |
| SCHEMBL29030571 | 0.80 | NLRP3 (0.61) | NLRP3IL1B | |
| SCHEMBL31681928 | 0.76 | NLRP3 (0.55) | NLRP3IL1B | |
| SCHEMBL25859161 | 0.74 | NLRP3 (0.46) | NLRP3IL1B | |
| SCHEMBL25858493 | 0.73 | BACE1 (0.33) | NLRP3 | |
| SCHEMBL25856423 | 0.73 | NLRP3 (0.30) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |