Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 11/20 | 0.46 |
| ▸ | IL1B | P01584 | 6/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857850 | 0.84 | NLRP3 (0.42) | NLRP3IL1BTNFCHRM1EGLN1 | |
| SCHEMBL25859262 | 0.84 | IL1B (0.43) | NLRP3IL1BTNFCHRM1 | |
| SCHEMBL25303261 | 0.80 | IL1B (0.70) | NLRP3IL1B | |
| SCHEMBL25262152 | 0.80 | IL1B (0.70) | NLRP3IL1B | |
| SCHEMBL30488618 | 0.80 | IL1B (0.70) | NLRP3IL1B | |
| SCHEMBL25859574 | 0.80 | NLRP3 (0.43) | NLRP3IL1BTNFCHRM1 | |
| SCHEMBL25859022 | 0.75 | EGLN1 (0.37) | NLRP3EGLN1 | |
| SCHEMBL25858377 | 0.74 | NLRP3 (0.35) | NLRP3IL1B | |
| SCHEMBL25859445 | 0.74 | NLRP3 (0.35) | NLRP3IL1B | |
| SCHEMBL30833929 | 0.71 | NLRP3 (0.48) | NLRP3IL1BTNFCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |