Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.64 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857612 | 0.87 | TOP2A (0.52) | ADORA2ATOP2AADORA1HTR2CBRD4 | |
| SCHEMBL25857595 | 0.86 | ADORA2A (0.64) | ADORA2AADORA1KDM4EALDH1A1LMNA | |
| SCHEMBL29435895 | 0.79 | ADORA2A (0.52) | ADORA2AADORA1BRD4 | |
| SCHEMBL25307292 | 0.79 | ADORA2A (0.52) | ADORA2AADORA1BRD4 | |
| SCHEMBL2820509 | 0.78 | TOP2A (0.52) | ADORA2ATOP2AADORA1HTR2CBRD4 | |
| SCHEMBL25857400 | 0.78 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL2816022 | 0.77 | TOP2A (0.51) | ADORA2ATOP2AADORA1HTR2CBRD4 | |
| SCHEMBL25857423 | 0.75 | TOP2A (0.51) | ADORA2ATOP2AADORA1HTR2CBRD4 | |
| SCHEMBL2816349 | 0.73 | KDM4E (0.63) | ADORA2ATOP2AADORA1HTR2CBRD4 | |
| SCHEMBL2816600 | 0.73 | TOP2A (0.52) | ADORA2ATOP2AADORA1HTR2CBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165165-A1 | BENZOIMIDAZOPYRAZINE-3-CARBOXAMIDE COMPOUND TARGETING A2A AND ANTI-TUMOR IMMUNOLOGICAL FUNCTION THEREOF | 中山大学 | 2023-09-07 | — | — | WO | disclosed |
| WO-2023130701-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | 中山大学 | 2023-07-13 | — | — | WO | disclosed |