SCHEMBL25858533

SCHEMBL25858533

C/C=C(/C)n1ccc(N)nc1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3A Q14432 3/20 0.36
PDE4D Q08499 1/20 0.36
SLC29A1 Q99808 1/20 0.36
LMNA P02545 3/20 0.35
THRB P10828 1/20 0.35
MTOR P42345 1/20 0.35
MDM2 Q00987 1/20 0.35
NCOA1 Q15788 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35
CACNA1F O60840 2/20 0.34
ALB P02768 2/20 0.34
MAPT P10636 2/20 0.34
CACNA1D Q01668 2/20 0.34
CACNA1S Q13698 2/20 0.34
CACNA1C Q13936 2/20 0.34
FGFR1 P11362 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
POLA1 P09884 1/20 0.32
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25793694 0.87 PDE3A (0.33) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL21186 0.81 NOTUM (0.43) PDE3APDE4DSLC29A1LMNATHRB
Methane SCHEMBL27916787 0.80 NOTUM (0.42) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL20801121 0.80 FGFR1 (0.37) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL5349324 0.79 LMNA (0.34) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL27740855 0.79 NOTUM (0.41) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL22540523 0.79 LMNA (0.35) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL10679054 0.76 LMNA (0.38) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL27819780 0.76 PARP1 (0.43) PDE3APDE4DSLC29A1LMNATHRB
SCHEMBL21173516 0.74 PDE4D (0.31) PDE3APDE4DSLC29A1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023103150-A1 DESIGN METHOD, APPARATUS AND DEVICE FOR ELECTROLYTE, AND MEDIUM AND PROGRAM PRODUCT 清华大学 2023-06-15 WO disclosed