⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21227827 | 0.76 | TAAR1 (0.33) | — | |
| SCHEMBL19337478 | 0.76 | TAAR1 (0.37) | — | |
| SCHEMBL30369685 | 0.72 | NPSR1 (0.44) | — | |
| SCHEMBL597339 | 0.72 | NPSR1 (0.44) | — | |
| SCHEMBL29293271 | 0.71 | KCNH2 (0.36) | — | |
| SCHEMBL18597323 | 0.68 | CYP3A4 (0.42) | — | |
| SCHEMBL15701362 | 0.67 | TSHR (0.37) | — | |
| SCHEMBL13525418 | 0.67 | HMGCR (0.36) | — | |
| SCHEMBL24455111 | 0.67 | SHBG (0.38) | — | |
| SCHEMBL21386521 | 0.65 | NPSR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133217-A1 | 2-(INDAZOL-5-YL)-6-(PIPERIDIN-4-YL)-1,7-NAPHTHYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |