SCHEMBL25859487

SCHEMBL25859487

CC(C(=O)c1ccc2c(c1)OCO2)N(C)C(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.55
CTNNB1 P35222 1/20 0.52
WNT3A P56704 1/20 0.52
RAB9A P51151 6/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 1/20 0.50
NPC1 O15118 5/20 0.48
MAPT P10636 2/20 0.48
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
PKM P14618 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25859869 1.00 HPGD (0.55) HPGDCTNNB1WNT3ARAB9AALDH1A1
SCHEMBL25859863 0.88 CASP3 (0.50) HPGDCTNNB1WNT3ARAB9AALDH1A1
SCHEMBL25860114 0.88 CASP3 (0.50) HPGDCTNNB1WNT3ARAB9AALDH1A1
SCHEMBL25171141 0.87 ALDH1A1 (0.55) HPGDCTNNB1WNT3ARAB9AALDH1A1
SCHEMBL25171142 0.87 ALDH1A1 (0.55) HPGDCTNNB1WNT3ARAB9AALDH1A1
SCHEMBL25171143 0.87 ALDH1A1 (0.55) HPGDCTNNB1WNT3ARAB9AALDH1A1
SCHEMBL25860112 0.86 NPC1 (0.53) HPGDCTNNB1WNT3ARAB9AALDH1A1
SCHEMBL25859862 0.86 NPC1 (0.53) HPGDCTNNB1WNT3ARAB9AALDH1A1
SCHEMBL25859489 0.86 NPC1 (0.53) HPGDCTNNB1WNT3ARAB9AALDH1A1
SCHEMBL25306490 0.84 MEN1 (0.52) HPGDRAB9AALDH1A1MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137453-A1 PRODRUGS OF 3,4-METHYLENEDIOXY-N-METHCATHINONE AND USES THEREOF TERRAN BIOSCIENCES INC. (US) 2023-07-20 WO disclosed