SCHEMBL25859594

SCHEMBL25859594

C=C1COc2c(ccc(F)c2F)C1[C@](N)(O)C(=O)OCC

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 1/20 0.31
MGAM O43451 1/20 0.31
AMY1A P0DUB6 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
MAPT P10636 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25859593 0.80
SCHEMBL25859235 0.78 POLB (0.38) MGAMAMY1AGAASIMGAM2
SCHEMBL25854710 0.76 MGAM (0.32) MGAMAMY1AGAASIMGAM2
SCHEMBL25854712 0.69
SCHEMBL25526400 0.69 PRMT5 (0.32)
SCHEMBL25526403 0.66 MGAM (0.32) MGAMAMY1AGAASIMGAM2
SCHEMBL25859595 0.62 TSHR (0.34) OPRL1MGAMAMY1AGAASI
SCHEMBL23977061 0.61 KDM4C (0.38) OPRL1
SCHEMBL6940594 0.58 HDAC4 (0.45) MAPT
SCHEMBL14722051 0.57 NLRP3 (0.41) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227437-A1 IMMUNOMODULATOR HITGEN INC (CN) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227437-A1 IMMUNOMODULATOR IL17A, IL2, IL2RA OPRL1 2948/4885MGAM 2305/4885AMY1A 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.