SCHEMBL25859595

SCHEMBL25859595

CCOC(=O)CC1c2ccc(F)c(F)c2OCC12CC2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SIGMAR1 Q99720 3/20 0.33
HTR1A P08908 1/20 0.33
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
TMEM97 Q5BJF2 1/20 0.33
NLRP3 Q96P20 1/20 0.33
MGAM O43451 1/20 0.32
AMY1A P0DUB6 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MIF P14174 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25529237 0.83 PPARG (0.32)
SCHEMBL25526544 0.76 KDM4E (0.35) TSHRHSD17B10L3MBTL1SIGMAR1HTR1A
SCHEMBL22992472 0.69 OPRM1 (0.38) L3MBTL1SIGMAR1MEN1KMT2AALDH1A1
SCHEMBL25854095 0.67
SCHEMBL22992564 0.67 CYP1A2 (0.44) TSHRHSD17B10SIGMAR1GAAMEN1
SCHEMBL25529315 0.67
SCHEMBL1339687 0.66 CYP11B1 (0.51) NLRP3ALDH1A1CYP1A2HSD17B1CYP11B1
SCHEMBL10032971 0.64 CYP11B1 (0.39) TSHRHSD17B10L3MBTL1NLRP3GAA
SCHEMBL25526403 0.64 MGAM (0.32) MGAMAMY1AGAASIMGAM2
SCHEMBL25526501 0.64 FFAR4 (0.32) GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227437-A1 IMMUNOMODULATOR HITGEN INC (CN) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227437-A1 IMMUNOMODULATOR IL17A, IL2, IL2RA TSHR 3265/4885HSD17B10 594/4885L3MBTL1 4577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.