Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27654124 | 0.85 | CYP1A2 (0.55) | CYP1A2TSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL27573300 | 0.85 | CYP1A2 (0.55) | CYP1A2TSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7805366 | 0.85 | CYP1A2 (0.55) | CYP1A2TSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL19302979 | 0.84 | CYP1A2 (0.57) | CYP1A2TSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL10519958 | 0.83 | CYP1A2 (0.56) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL30331074 | 0.82 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL11461676 | 0.82 | CYP1A2 (0.54) | CYP1A2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7263695 | 0.82 | CYP1A2 (1.00) | CYP1A2TSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL3259894 | 0.82 | CYP1A2 (0.68) | CYP1A2TSHRALDH1A1L3MBTL1MEN1 | |
| SCHEMBL185472 | 0.82 | CYP1A2 (0.68) | CYP1A2TSHRALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058471-B2 | Method for producing optically active hydroxycarboxylic acid derivatives or salts thereof | KANEKA CORPORATION (JP) | 2011-11-15 | — | — | US | disclosed |
| US-20100191011-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXYCARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | KANEKA CORPORATION (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-2053032-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXYCARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | Kaneka Corporation (JP) | 2009-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100191011-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXYCARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | DHPS, HAAO, HCAR2 | CYP1A2 826/4885TSHR 4310/4885ALDH1A1 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.