SCHEMBL7805366

SCHEMBL7805366

CC(=O)CC(O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.55
TSHR P16473 1/20 0.55
ALDH1A1 P00352 5/20 0.53
TDP1 Q9NUW8 1/20 0.46
HTT P42858 1/20 0.43
KMT2A Q03164 3/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KCNH2 Q12809 1/20 0.41
CTSD P07339 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27573300 1.00 CYP1A2 (0.55) CYP1A2TSHRALDH1A1TDP1HTT
SCHEMBL27654124 1.00 CYP1A2 (0.55) CYP1A2TSHRALDH1A1TDP1HTT
SCHEMBL258598 0.85 CYP1A2 (0.69) CYP1A2TSHRALDH1A1TDP1HTT
SCHEMBL6259348 0.81 ALDH1A1 (0.53) CYP1A2TSHRALDH1A1TDP1KMT2A
SCHEMBL30331074 0.81 CYP1A2 (0.54) CYP1A2TSHRALDH1A1TDP1KMT2A
SCHEMBL11461676 0.81 CYP1A2 (0.54) CYP1A2TSHRALDH1A1TDP1KMT2A
SCHEMBL27897667 0.81 CYP1A2 (0.49) CYP1A2TSHRALDH1A1TDP1HTT
SCHEMBL7153686 0.80 CYP1A2 (0.53) CYP1A2TSHRALDH1A1TDP1KMT2A
SCHEMBL267829 0.80 CYP1A2 (0.53) CYP1A2TSHRALDH1A1TDP1KMT2A
SCHEMBL14599491 0.80 CYP1A2 (0.53) CYP1A2TSHRALDH1A1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1332161-A Method for preparing sulfamine urea compound AMERICAN CYANAMID CO (US) 2002-01-23 CN claimed
EP-0852224-B1 Aryne intermediates towards the preparation of herbicidal sulfamoyl urea and a process for their preparation AMERICAN CYANAMID CO (US) 2001-10-31 EP claimed
US-5856576-A Aryne intermediates and a process for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1999-01-05 US claimed
CN-1187485-A aryne intermediate and preparation method thereof AMERICAN CYANAMID CO (US) 1998-07-15 CN claimed
EP-0852224-A1 Aryne intermediates towards the preparation of herbicidal sulfamoyl urea and a process for their preparation American Cyanamid Company (US) 1998-07-08 EP claimed
CN-118530159-B Method for synthesizing 5-bromoisatin or 6-bromoisatin 山东仁一生物科技有限责任公司 2024-09-20 CN disclosed
CN-118530159-A Method for synthesizing 5-bromoisatin or 6-bromoisatin 山东仁一生物科技有限责任公司 2024-08-23 CN disclosed
CN-109776371-B Chiral tridentate ligand of nitrogen-containing heterocyclic propane and preparation method thereof 北京化工大学 2020-12-25 CN disclosed
CN-100491317-C Method for prepring compound of beta hydroxyketone in supercritical liquid of carbon dioxide SHAANXI TEACHER S UNIVERSITY (CN) 2009-05-27 CN disclosed
CN-100415703-C Process for preparing optically active beta-hydroxyketone UNIV WUHAN (CN) 2008-09-03 CN disclosed
CN-101092338-A Method for prepring compound of beta hydroxyketone in supercritical liquid of carbon dioxide SHAANXI TEACHER S UNIV (CN) 2007-12-26 CN disclosed
CN-1331835-C Preparation method of optically active beta-hydroxy ketone UNIV WUHAN (CN) 2007-08-15 CN disclosed
CN-1827573-A Process for preparing optically active beta-hydroxyketone UNIV WUHAN (CN) 2006-09-06 CN disclosed
CN-1785950-A Preparation method of optically active beta-hydroxy ketone UNIV WUHAN (CN) 2006-06-14 CN disclosed