Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL2585997 | 0.88 | SLC7A5 (0.56) | SLC7A5ITGB3ITGA2BLNPEPTHRB | |
| Tyrosine SCHEMBL3121863 | 0.88 | SLC7A5 (0.56) | SLC7A5ITGB3ITGA2BLNPEPTHRB | |
| Tyrosine SCHEMBL1921852 | 0.87 | SLC7A5 (0.55) | SLC7A5ITGB3ITGA2BLNPEPTHRB | |
| Tyrosine SCHEMBL7795413 | 0.85 | SLC7A5 (0.55) | SLC7A5MMEACECPA1ACE2 | |
| Tyrosine SCHEMBL2723437 | 0.85 | SLC7A5 (0.57) | SLC7A5ITGB3ITGA2BLNPEPTHRB | |
| Tyrosine SCHEMBL11404581 | 0.84 | SLC7A5 (0.49) | SLC7A5ITGB3ITGA2BLNPEPTHRB | |
| SCHEMBL14562523 | 0.84 | SLC7A5 (0.50) | SLC7A5MMEACECPA1ACE2 | |
| Tyrosine SCHEMBL5666706 | 0.84 | SLC7A5 (0.56) | SLC7A5ITGB3ITGA2BLNPEPTHRB | |
| Tyrosine SCHEMBL6460601 | 0.83 | SLC7A5 (0.50) | SLC7A5ITGB3ITGA2BLNPEPTHRB | |
| SCHEMBL3920416 | 0.83 | SLC7A5 (0.51) | SLC7A5ITGB3ITGA2BLNPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063195-B2 | Mutations in a toll-like receptor motif in the NS4B of classical swine fever virus strain brescia influences virulence in swine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2011-11-22 | — | — | US | disclosed |
| WO-2010135054-A2 | MUTATIONS IN A TOLL-LIKE RECEPTOR MOTIF IN THE NS4B OF CLASSICAL SWINE FEVER VIRUS SKIN BRESCIA INFLUENCES VIRULENCE IN SWINE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2010-11-25 | — | — | WO | disclosed |
| US-20100297175-A1 | Mutations in a toll-like receptor motif in the NS4B of classical swine fever virus strain brescia influences virulence in swine | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2010-11-25 | — | — | US | disclosed |