Tyrosine

Tyrosine

SCHEMBL6460601

CCCC[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)OC(=O)[C@@H](N)Cc1ccccc1.N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.50
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
ALPI P09923 1/20 0.46
PKM P14618 1/20 0.46
PTGS1 P23219 1/20 0.46
XIAP P98170 1/20 0.46
OPRM1 P35372 2/20 0.44
OPRD1 P41143 2/20 0.44
MMP2 P08253 1/20 0.44
LNPEP Q9UIQ6 3/20 0.42
ERAP2 Q6P179 2/20 0.42
ERAP1 Q9NZ08 1/20 0.42
THRB P10828 1/20 0.42
GSR P00390 1/20 0.42
TYR P14679 2/20 0.41
LTA4H P09960 1/20 0.41
ANPEP P15144 1/20 0.40
DAGLA Q9Y4D2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL6460603 0.92 SLC7A5 (0.58) SLC7A5ITGB3ITGA2BALPIPKM
Tyrosine SCHEMBL7196997 0.90 SLC7A5 (0.50) SLC7A5ITGB3ITGA2BALPIPKM
Tyrosine SCHEMBL1921852 0.87 SLC7A5 (0.55) SLC7A5ITGB3ITGA2BALPIPKM
Tyrosine SCHEMBL2723437 0.87 SLC7A5 (0.57) SLC7A5ITGB3ITGA2BALPIPKM
Tyrosine SCHEMBL22654492 0.87 SLC7A5 (0.67) SLC7A5ITGB3ITGA2BALPIPKM
Tyrosine SCHEMBL27074660 0.87 SLC7A5 (0.67) SLC7A5ITGB3ITGA2BALPIPKM
Tyrosine SCHEMBL3121863 0.86 SLC7A5 (0.56) SLC7A5ITGB3ITGA2BALPIPKM
Tyrosine SCHEMBL7701661 0.85 OPRD1 (0.42) SLC7A5OPRM1OPRD1LNPEPERAP2
SCHEMBL3920416 0.85 SLC7A5 (0.51) SLC7A5ITGB3ITGA2BMMP2LNPEP
SCHEMBL237821 0.84 MMP2 (0.58) SLC7A5ITGB3ITGA2BALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050042676-A1 Characterising polypeptides ELECTROPHORETICS LIMITED (GB) 2005-02-24 US disclosed