SCHEMBL25860272

SCHEMBL25860272

CC(C)[C@H](N)C(=O)N(C)[C@H](C)C(=O)c1ccc2c(c1)OCO2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
ALDH1A1 P00352 4/20 0.46
MAPK1 P28482 1/20 0.46
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
HPGD P15428 4/20 0.43
SRD5A2 P31213 1/20 0.42
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
PKM P14618 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 1/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40
MAPT P10636 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25863021 1.00 MEN1 (0.47) MEN1KMT2AALDH1A1MAPK1NPC1
SCHEMBL25859936 1.00 MEN1 (0.47) MEN1KMT2AALDH1A1MAPK1NPC1
SCHEMBL25863045 0.91 ALDH1A1 (0.44) MEN1KMT2AALDH1A1MAPK1NPC1
SCHEMBL25860270 0.90 ALDH1A1 (0.48) MEN1KMT2AALDH1A1MAPK1NPC1
SCHEMBL25859935 0.90 ALDH1A1 (0.48) MEN1KMT2AALDH1A1MAPK1NPC1
SCHEMBL25859940 0.89 TAS1R3 (0.49) MEN1KMT2AALDH1A1MAPK1NPC1
SCHEMBL25860277 0.89 TAS1R3 (0.49) MEN1KMT2AALDH1A1MAPK1NPC1
SCHEMBL25859533 0.88 ALDH1A1 (0.51) MEN1KMT2AALDH1A1MAPK1NPC1
SCHEMBL25863041 0.86 HPGD (0.45) MEN1KMT2AALDH1A1MAPK1NPC1
SCHEMBL25860275 0.84 TAS1R3 (0.47) MEN1KMT2AALDH1A1MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137453-A1 PRODRUGS OF 3,4-METHYLENEDIOXY-N-METHCATHINONE AND USES THEREOF TERRAN BIOSCIENCES INC. (US) 2023-07-20 WO disclosed