SCHEMBL25860284

SCHEMBL25860284

C[C@H](C(=O)c1ccc2c(c1)OCO2)N(C)C(=O)[C@@H](N)CC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
MAPK1 P28482 1/20 0.45
HPGD P15428 2/20 0.45
PKM P14618 1/20 0.43
MAPK9 P45984 1/20 0.43
CTNNB1 P35222 1/20 0.41
WNT3A P56704 1/20 0.41
KMT2A Q03164 4/20 0.41
SRD5A2 P31213 1/20 0.41
TAS1R3 Q7RTX0 2/20 0.41
TAS1R1 Q7RTX1 2/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 3/20 0.41
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25859950 1.00 ALDH1A1 (0.45) ALDH1A1MAPK1HPGDPKMMAPK9
SCHEMBL25859636 1.00 ALDH1A1 (0.45) ALDH1A1MAPK1HPGDPKMMAPK9
SCHEMBL25863041 0.90 HPGD (0.45) ALDH1A1MAPK1HPGDPKMCTNNB1
SCHEMBL25859944 0.89 HPGD (0.43) ALDH1A1MAPK1HPGDPKMMAPK9
SCHEMBL25859638 0.89 HPGD (0.43) ALDH1A1MAPK1HPGDPKMMAPK9
SCHEMBL25860293 0.89 HPGD (0.43) ALDH1A1MAPK1HPGDPKMMAPK9
SCHEMBL25859939 0.87 TAS1R3 (0.47) ALDH1A1MAPK1HPGDPKMKMT2A
SCHEMBL25860275 0.87 TAS1R3 (0.47) ALDH1A1MAPK1HPGDPKMKMT2A
SCHEMBL25863025 0.87 TAS1R3 (0.47) ALDH1A1MAPK1HPGDPKMKMT2A
SCHEMBL25859935 0.86 ALDH1A1 (0.48) ALDH1A1MAPK1HPGDPKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137453-A1 PRODRUGS OF 3,4-METHYLENEDIOXY-N-METHCATHINONE AND USES THEREOF TERRAN BIOSCIENCES INC. (US) 2023-07-20 WO disclosed