Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528305 | 0.84 | AKR1B1 (0.36) | AKR1B1PPARGPPARDLTB4RLTB4R2 | |
| SCHEMBL25859350 | 0.81 | HTR2A (0.40) | AKR1B1KDM4CALK | |
| SCHEMBL25523284 | 0.81 | HTR2B (0.39) | AKR1B1KDM4CALK | |
| SCHEMBL25859676 | 0.79 | AKR1B1 (0.32) | AKR1B1PPARGPPARDLTB4RLTB4R2 | |
| SCHEMBL25527859 | 0.78 | HSD11B1 (0.37) | AKR1B1HSD11B1 | |
| SCHEMBL25526501 | 0.76 | FFAR4 (0.32) | PPARGPPARDLTB4RLTB4R2FFAR1 | |
| SCHEMBL25529237 | 0.76 | PPARG (0.32) | PPARGPPARD | |
| SCHEMBL22992537 | 0.75 | PSEN1 (0.38) | AKR1B1HSD11B1 | |
| SCHEMBL22992539 | 0.75 | PSEN1 (0.38) | AKR1B1HSD11B1 | |
| SCHEMBL22992538 | 0.75 | PSEN1 (0.38) | AKR1B1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227437-A1 | IMMUNOMODULATOR | HITGEN INC (CN) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227437-A1 | IMMUNOMODULATOR | IL17A, IL2, IL2RA | AKR1B1 868/4885PPARG 432/4885PPARD 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.