Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13498163 | 0.91 | TSHR (0.51) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL258551 | 0.82 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13109364 | 0.80 | TSHR (0.42) | TSHRHPGD | |
| SCHEMBL29023701 | 0.78 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL2403438 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL19138875 | 0.76 | TSHR (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13498165 | 0.75 | PKM (0.36) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6429759 | 0.74 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL40904 | 0.74 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL20988013 | 0.73 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063123-B2 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-11-22 | — | — | US | disclosed |
| US-20070225414-A1 | Phosphorus-containing mixtures, a process for their preparation and their use | CLARIANT INTERNATIONAL LTD | 2007-09-27 | — | — | US | disclosed |