Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361879 | 0.90 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8362507 | 0.90 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8359498 | 0.90 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8362138 | 0.90 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8361669 | 0.90 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8358120 | 0.90 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL15967407 | 0.87 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL2362556 | 0.85 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL15967403 | 0.84 | ALDH1A1 (0.37) | ALDH1A1 | |
| Methyl Alcohol SCHEMBL29212516 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084022-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. (NL) | 2025-03-13 | — | — | US | disclosed |
| US-12180145-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | SYNAFFIX B.V. (NL) | 2024-12-31 | — | — | US | disclosed |
| US-20230102685-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. (NL) | 2023-03-30 | — | — | US | disclosed |
| US-11358921-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | SYNAFFIX B.V. (NL) | 2022-06-14 | — | — | US | disclosed |
| US-20200048174-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. (NL) | 2020-02-13 | — | — | US | disclosed |
| EP-3604264-A1 | FUSED CYCLOOCTYNE COMPOUNDS | SynAffix B.V. (NL) | 2020-02-05 | — | — | EP | disclosed |
| EP-2894142-B1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX BV (NL) | 2019-06-12 | — | — | EP | disclosed |
| US-10239807-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | SYNAFFIX B.V. (NL) | 2019-03-26 | — | — | US | disclosed |
| US-20160214917-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. (NL) | 2016-07-28 | — | — | US | disclosed |
| EP-2563753-B9 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX BV (NL) | 2016-07-06 | — | — | EP | disclosed |
| EP-2563753-B3 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX BV (NL) | 2016-01-06 | — | — | EP | disclosed |
| US-9222940-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | SYNAFFIX B.V. (NL) | 2015-12-29 | — | — | US | disclosed |
| EP-2894142-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SynAffix B.V. (NL) | 2015-07-15 | — | — | EP | disclosed |
| US-20150125892-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. (NL) | 2015-05-07 | — | — | US | disclosed |
| EP-2563753-B1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX BV (NL) | 2014-11-05 | — | — | EP | disclosed |
| US-8859629-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | SYNAFFIX B.V. (NL) | 2014-10-14 | — | — | US | disclosed |
| US-20130137763-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. | 2013-05-30 | — | — | US | disclosed |
| EP-2563753-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SynAffix B.V. (NL) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011136645-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | STICHTING KATHOLIEKE UNIVERSITEIT, MORE PARTICULARLY RADBOUD UNIVERSITY NIJMEGEN (NL) | 2011-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137763-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | MPI, SQLE, TACR3 | ALDH1A1 1882/4885 |
| US-11358921-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | MPI, SQLE, TACR3 | ALDH1A1 1882/4885 |
| US-10239807-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | MPI, SQLE, TACR3 | ALDH1A1 1882/4885 |
| US-20230102685-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | MPI, SQLE, TACR3 | ALDH1A1 1882/4885 |
| US-20250084022-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | MPI, SQLE, TACR3 | ALDH1A1 1882/4885 |
| US-20200048174-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | MPI, SQLE, TACR3 | ALDH1A1 1882/4885 |
| US-20160214917-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | MPI, SQLE, TACR3 | ALDH1A1 1882/4885 |
| US-20150125892-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | MPI, SQLE, TACR3 | ALDH1A1 1882/4885 |
| US-12180145-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | MPI, SQLE, TACR3 | ALDH1A1 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.