SCHEMBL2586204

SCHEMBL2586204

N[C@@H](Cc1cnc[nH]1)C(=O)OC(=O)[C@@H]1CCCN1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.50
▸ SLC7A5 Q01650 1/20 0.50
▸ DPP4 P27487 1/20 0.47
▸ DPP7 Q9UHL4 1/20 0.42
▸ NLN Q9BYT8 3/20 0.40
▸ HRH2 P25021 1/20 0.40
▸ HRH1 P35367 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11606914 1.00 CYP3A4 (0.50) CYP3A4SLC7A5DPP4DPP7NLN
SCHEMBL1537285 0.80 CYP3A4 (0.71) CYP3A4SLC7A5
SCHEMBL163444 0.80 CYP3A4 (0.71) CYP3A4SLC7A5
SCHEMBL27273945 0.80 CYP3A4 (0.50) CYP3A4SLC7A5DPP4NLN
Hydrochloric Acid SCHEMBL28331180 0.79 CYP3A4 (0.69) CYP3A4SLC7A5
SCHEMBL28328192 0.77 CYP3A4 (0.67) CYP3A4SLC7A5
SCHEMBL3726266 0.76 CTSC (0.50) CYP3A4SLC7A5DPP4DPP7
SCHEMBL2478803 0.76 CTSC (0.50) CYP3A4SLC7A5DPP4DPP7
SCHEMBL498386 0.76 CTSC (0.50) CYP3A4SLC7A5DPP4DPP7
SCHEMBL5221763 0.76 CYP3A4 (0.65) CYP3A4SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333038-A Aspirin derivative, preparation method and application thereof in preventing cardiovascular and cerebrovascular diseases 湖北南博生物工程有限公司 2023-06-27 — — CN claimed
CN-111246859-B Pharmaceutical composition for preventing or treating diabetes containing zinc salt, cyclodipeptide-histidine proline and antidiabetic drug as effective component 诺麦塔制药有限公司 2022-05-03 — — CN claimed
CN-111246859-A Pharmaceutical composition for preventing or treating diabetes containing zinc salt, cyclodipeptide-histidine proline and antidiabetic drug as effective component 诺麦塔制药有限公司 2020-06-05 — — CN claimed
CN-101674842-A Compositions and methods for treating alzheimer's disease and dementia PREVENTIVE NUTRIENT COMPANY IN 2010-03-17 — — CN claimed
WO-2003099322-A2 IL-11 DERIVATIVES AND THERAPEUTIC USES THEREOF ISIS INNOVATION LIMITED (GB) 2003-12-04 — — WO claimed
CN-116803290-A Meat processing method capable of reducing content of bound heterocyclic amine 江南大学 2023-09-26 — — CN disclosed
CN-116333038-A Aspirin derivative, preparation method and application thereof in preventing cardiovascular and cerebrovascular diseases 湖北南博生物工程有限公司 2023-06-27 — — CN disclosed
CN-116333038-A Aspirin derivative, preparation method and application thereof in preventing cardiovascular and cerebrovascular diseases 湖北南博生物工程有限公司 2023-06-27 — — CN disclosed
CN-111246859-B Pharmaceutical composition for preventing or treating diabetes containing zinc salt, cyclodipeptide-histidine proline and antidiabetic drug as effective component 诺麦塔制药有限公司 2022-05-03 — — CN disclosed
EP-3684332-A1 VEGFR-FC FUSION PROTEIN FORMULATIONS Amgen Inc. (US) 2020-07-29 — — EP disclosed
CN-111246859-A Pharmaceutical composition for preventing or treating diabetes containing zinc salt, cyclodipeptide-histidine proline and antidiabetic drug as effective component 诺麦塔制药有限公司 2020-06-05 — — CN disclosed
EP-3502699-A1 METHODS FOR DIAGNOSING PANCREATIC CANCER Metanomics Health GmbH (DE) 2019-06-26 — — EP disclosed
WO-2002064621-A3 HISTIDINE PROLINE RICH GLYCOPROTEIN (HPRG) AS AN ANTI-ANGIOGENIC AND ANTI-TUMOR AGENT ATTENUON LLC (US) 2003-05-30 — — WO disclosed
WO-2002064621-A3 HISTIDINE PROLINE RICH GLYCOPROTEIN (HPRG) AS AN ANTI-ANGIOGENIC AND ANTI-TUMOR AGENT ATTENUON LLC (US) 2003-05-30 — — WO disclosed
US-20030082740-A1 Histidine proline rich glycoprotein (HPRG) as an anti-angiogenic and anti-tumor agent ATTENUON, LLC 2003-05-01 — — US disclosed
US-20030082740-A1 Histidine proline rich glycoprotein (HPRG) as an anti-angiogenic and anti-tumor agent ATTENUON, LLC 2003-05-01 — — US disclosed
US-20030082740-A1 Histidine proline rich glycoprotein (HPRG) as an anti-angiogenic and anti-tumor agent ATTENUON, LLC 2003-05-01 — — US disclosed
WO-2002064621-A2 HISTIDINE PROLINE RICH GLYCOPROTEIN (HPRG) AS AN ANTI-ANGIOGENIC AND ANTI-TUMOR AGENT ATTENUON, LLC (US) 2002-08-22 — — WO disclosed
WO-2002064621-A2 HISTIDINE PROLINE RICH GLYCOPROTEIN (HPRG) AS AN ANTI-ANGIOGENIC AND ANTI-TUMOR AGENT ATTENUON, LLC (US) 2002-08-22 — — WO disclosed
WO-2002064621-A2 HISTIDINE PROLINE RICH GLYCOPROTEIN (HPRG) AS AN ANTI-ANGIOGENIC AND ANTI-TUMOR AGENT ATTENUON, LLC (US) 2002-08-22 — — WO disclosed
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