Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2478803 | 1.00 | CTSC (0.50) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL3726266 | 1.00 | CTSC (0.50) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL10757105 | 0.92 | HTR2C (0.45) | CTSCALPIPKMPTGS1XIAP | |
| Tyrosine SCHEMBL9686139 | 0.91 | SLC7A5 (0.50) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL10940484 | 0.91 | CTSC (0.45) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL4205064 | 0.89 | SLC7A5 (0.44) | CTSCSLC7A5HTR2CHTR2BDPP4 | |
| SCHEMBL11558863 | 0.86 | CTSC (0.51) | CTSCHTR2CHTR2BDPP4DPP8 | |
| SCHEMBL11560702 | 0.85 | CTSC (0.48) | CTSCHTR2CHTR2BDPP4DPP8 | |
| Phenylalanine SCHEMBL5672080 | 0.84 | SLC7A5 (0.51) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL17728303 | 0.84 | SLC7A5 (0.46) | CTSCSLC7A5HTR2CHTR2BDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734541-B1 | NOVEL IL-17R-ECD MUTANTS | THE NAT INST FOR BIOTECHNOLOGY IN THE NEGEV LTD (IL) | 2017-09-06 | — | — | EP | claimed |
| CN-102837341-B | Mildew-proof and mothproof treatment method for bamboo materials | UNIV CENTRAL SOUTH FORESTRY | 2014-08-13 | — | — | CN | claimed |
| EP-1768490-A2 | SYSTEMS AND METHODS FOR EX-VIVO ORGAN CARE | Transmedics, Inc. (US) | 2007-04-04 | — | — | EP | claimed |
| EP-1575642-A4 | MULTI-BALLOON CATHETER WITH HYDROGEL COATING | BOSTON SCIENT LTD (BB) | 2007-03-07 | — | — | EP | claimed |
| WO-2006042138-A2 | SYSTEMS AND METHODS FOR EX-VIVO ORGAN CARE | TRANSMEDICS, INC. (US) | 2006-04-20 | — | — | WO | claimed |
| EP-1575642-A2 | MULTI-BALLOON CATHETER WITH HYDROGEL COATING | Boston Scientific Limited (BB) | 2005-09-21 | — | — | EP | claimed |
| WO-2004028587-A2 | MULTI-BALLOON CATHETER WITH HYDROGEL COATING | BOSTON SCIENTIFIC LIMITED (BB) | 2004-04-08 | — | — | WO | claimed |
| EP-0139592-B1 | PROCESS AND APPARATUS FOR THE PRODUCTION OF AMINOACIDS BY FERMENTATION | LES PRODUITS ORGANIQUES DU SANTERRE ORSAN (FR) | 1992-03-25 | — | — | EP | claimed |
| CN-118340216-A | Medicinal and edible plant composition with uric acid reducing function and preparation method and application thereof | 湖南楚茗茶业有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118043316-A | Factor XIIa inhibitors | 卢纳克治疗有限公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-4347578-A1 | FACTOR XIIA INHIBITORS | Lunac Therpeutics Ltd (GB) | 2024-04-10 | — | — | EP | disclosed |
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2022-09-29 | — | — | US | disclosed |
| EP-3773555-A1 | FACTOR XIIA INHIBITORS | University of Leeds (GB) | 2021-02-17 | — | — | EP | disclosed |
| CN-112165938-A | Factor XIIA inhibitors | 利兹大学 | 2021-01-01 | — | — | CN | disclosed |
| WO-1998029547-A1 | MODULATORS OF RADIAL GLIA-ASTROCYTE DIFFERENTIATION AND TRANSFORMATION, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 1998-07-09 | — | — | WO | disclosed |
| EP-0512066-A4 | CO-INDEPENDENT GROWTH MEDIUM FOR MAINTENANCE AND PROPAGATION OF CELLS | US HEALTH (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5185248-A | Farnesylation of peptide substrate; detecting amount of labeled farnesyl residue in substrate | E. R. SQUIBB & SONS, INC. (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0512066-A1 | CO-INDEPENDENT GROWTH MEDIUM FOR MAINTENANCE AND PROPAGATION OF CELLS. | US HEALTH (US) | 1992-11-11 | — | — | EP | disclosed |
| WO-1991010726-A1 | CO-INDEPENDENT GROWTH MEDIUM FOR MAINTENANCE AND PROPAGATION OF CELLS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1991-07-25 | — | — | WO | disclosed |
| WO-1990007713-A1 | MOLECULAR RECOGNITION UNITS | CYTOGEN CORPORATION (US) | 1990-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | F11, F13B, F12 | CTSC 725/4885ALPI 532/4885PKM 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.