Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586204 | 0.80 | CYP3A4 (0.50) | CYP3A4SLC7A5NLNDPP4 | |
| SCHEMBL11606914 | 0.80 | CYP3A4 (0.50) | CYP3A4SLC7A5NLNDPP4 | |
| SCHEMBL27448784 | 0.79 | TRHR (0.49) | REN | |
| SCHEMBL27639586 | 0.79 | TRHR (0.49) | REN | |
| SCHEMBL29792521 | 0.78 | EPHX2 (0.51) | CYP3A4SLC7A5REN | |
| SCHEMBL31339185 | 0.78 | EPHX2 (0.51) | CYP3A4SLC7A5REN | |
| SCHEMBL31339177 | 0.78 | EPHX2 (0.51) | CYP3A4SLC7A5REN | |
| SCHEMBL27504185 | 0.78 | TRHR (0.59) | REN | |
| SCHEMBL27273950 | 0.77 | CTSC (0.37) | REN | |
| SCHEMBL27913326 | 0.76 | CYP3A4 (0.69) | CYP3A4SLC7A5NLN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1020457-C | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | TANABE SEIYAKU CO (JP) | 1993-05-05 | — | — | CN | claimed |
| CN-85105655-A | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | — | 1987-01-28 | — | — | CN | claimed |
| CN-105949280-A | Preparation method of Taltirelin and intermediate thereof | 吉尔生化（上海）有限公司 | 2016-09-21 | — | — | CN | disclosed |
| CN-103665170-A | Peptide therapeutic conjugates and uses thereof | ANGIOCHEM INC | 2014-03-26 | — | — | CN | disclosed |
| CN-102348723-A | Peptide therapeutic agent conjugates and uses thereof | ANGIOCHEM INC | 2012-02-08 | — | — | CN | disclosed |
| CN-1214040-C | Peptide derivatives having thiazolyl-alanine residues | SHIONOGI & CO (JP) | 2005-08-10 | — | — | CN | disclosed |
| CN-1235610-A | Peptide derivatives having thiazolyl-alanine residues | SHIONOGI & CO (JP) | 1999-11-17 | — | — | CN | disclosed |
| CN-1020457-C | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | TANABE SEIYAKU CO (JP) | 1993-05-05 | — | — | CN | disclosed |
| CN-85105655-A | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | — | 1987-01-28 | — | — | CN | disclosed |