Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 16/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 16/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25862159 | 0.90 | DDB1 (0.51) | DDB1CRBNPRMT5WDR77 | |
| SCHEMBL25862803 | 0.89 | DDB1 (0.43) | DDB1CRBNPRKCGPRKCBPRKCA | |
| SCHEMBL25862453 | 0.84 | CRBN (0.44) | DDB1CRBN | |
| SCHEMBL29323602 | 0.81 | DDB1 (0.46) | DDB1CRBNGPR119PRMT5WDR77 | |
| SCHEMBL29322908 | 0.80 | DDB1 (0.47) | DDB1CRBNPRKCGPRKCBPRKCA | |
| SCHEMBL29323432 | 0.78 | DDB1 (0.45) | DDB1CRBNPRKCGPRKCBPRKCA | |
| SCHEMBL31692169 | 0.77 | DDB1 (0.61) | DDB1CRBNPRKCGPRKCBPRKCA | |
| SCHEMBL29079577 | 0.77 | DDB1 (0.40) | DDB1CRBNGPR119PRMT5WDR77 | |
| SCHEMBL21069281 | 0.76 | IRAK4 (0.44) | DDB1CRBNPRKCGPRKCBPRKCA | |
| SCHEMBL30893291 | 0.76 | IRAK4 (0.44) | DDB1CRBNPRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |