SCHEMBL29323602

SCHEMBL29323602

CC(C)(C)OC(=O)N1CCC(OCC#Cc2cccc3c2ccc2onc(C4CCC(=O)NC4=O)c23)CC1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 14/20 0.46
CRBN Q96SW2 14/20 0.46
GPR119 Q8TDV5 3/20 0.36
CETP P11597 1/20 0.34
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29331598 0.88 DDB1 (0.38) DDB1CRBN
SCHEMBL29323432 0.87 DDB1 (0.45) DDB1CRBNGPR119CETPPRMT5
SCHEMBL29323604 0.84 DDB1 (0.35) DDB1CRBN
SCHEMBL25862452 0.81 DDB1 (0.49) DDB1CRBNGPR119PRMT5WDR77
SCHEMBL25862159 0.81 DDB1 (0.51) DDB1CRBNPRMT5WDR77
SCHEMBL29322908 0.80 DDB1 (0.47) DDB1CRBNGPR119PRMT5WDR77
SCHEMBL29323600 0.79 GPR119 (0.38) GPR119CETP
SCHEMBL29323894 0.78 DDB1 (0.48) DDB1CRBN
SCHEMBL24508322 0.76 DDB1 (0.48) DDB1CRBNGPR119PRMT5WDR77
SCHEMBL29323101 0.75 DDB1 (0.44) DDB1CRBNGPR119CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed