Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.44 |
| ▸ | IL1B | P01584 | 11/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108798 | 0.91 | NLRP3 (0.45) | NLRP3IL1BCHEK2ALDH1A1 | |
| SCHEMBL30108809 | 0.91 | NLRP3 (0.45) | NLRP3IL1BCHEK2ALDH1A1 | |
| SCHEMBL25855237 | 0.90 | NLRP3 (0.44) | NLRP3IL1BCHEK2ALDH1A1 | |
| SCHEMBL25855252 | 0.84 | NLRP3 (0.53) | NLRP3IL1B | |
| SCHEMBL25297240 | 0.84 | NLRP3 (0.62) | NLRP3IL1BCHEK2 | |
| SCHEMBL30214066 | 0.84 | IL1B (0.56) | NLRP3IL1BCHEK2 | |
| SCHEMBL30488518 | 0.84 | NLRP3 (0.62) | NLRP3IL1BCHEK2 | |
| SCHEMBL25256054 | 0.84 | NLRP3 (0.62) | NLRP3IL1BCHEK2 | |
| SCHEMBL30213998 | 0.84 | IL1B (0.56) | NLRP3IL1BCHEK2 | |
| Formic Acid SCHEMBL31034906 | 0.80 | NLRP3 (0.58) | NLRP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |