Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 9/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 2/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30355652 | 0.88 | TDO2 (0.52) | TDO2GRM5NPC1HSD17B10MAPT | |
| SCHEMBL23523945 | 0.88 | TDO2 (0.52) | TDO2GRM5NPC1HSD17B10MAPT | |
| SCHEMBL30355426 | 0.84 | TDO2 (0.48) | TDO2GRM5NPC1MAPTRAB9A | |
| SCHEMBL23523779 | 0.84 | TDO2 (0.48) | TDO2GRM5NPC1MAPTRAB9A | |
| SCHEMBL30355720 | 0.84 | TDO2 (0.52) | TDO2GRM5NPC1MAPTRAB9A | |
| SCHEMBL23524081 | 0.84 | TDO2 (0.52) | TDO2GRM5NPC1MAPTRAB9A | |
| SCHEMBL25864495 | 0.83 | CASP3 (0.45) | TDO2CASP3SENP8SENP7SENP6 | |
| SCHEMBL25863145 | 0.78 | CASP3 (0.49) | CASP3SENP8SENP7SENP6GRM5 | |
| SCHEMBL23524176 | 0.77 | CASP3 (0.48) | CASP3SENP8SENP7SENP6GRM5 | |
| SCHEMBL23523828 | 0.77 | TDO2 (0.43) | TDO2CASP3GRM5GRM2SGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | TDO2 4580/4885CASP3 3079/4885SENP8 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.