Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25864980 | 0.83 | LMNA (0.34) | CYP51A1NPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL25864899 | 0.83 | LMNA (0.40) | CYP51A1NPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL25610825 | 0.78 | NAAA (0.46) | LMNACHRM2DRD3KCNH2CYP1A2 | |
| SCHEMBL25610830 | 0.78 | NAAA (0.46) | LMNACHRM2DRD3KCNH2CYP1A2 | |
| SCHEMBL18804783 | 0.78 | NAAA (0.38) | TSHR | |
| SCHEMBL25610819 | 0.77 | NAAA (0.44) | LMNACHRM2DRD3KCNH2CYP1A2 | |
| SCHEMBL25610907 | 0.77 | NAAA (0.44) | LMNACHRM2DRD3KCNH2CYP1A2 | |
| SCHEMBL19629038 | 0.77 | NAAA (0.44) | LMNACHRM2DRD3KCNH2CYP1A2 | |
| SCHEMBL26310718 | 0.77 | NAAA (0.44) | LMNACHRM2DRD3KCNH2CYP1A2 | |
| SCHEMBL18202122 | 0.77 | USP2 (0.41) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126006-A1 | CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF | 厦门赛诺邦格生物科技股份有限公司 | 2023-07-06 | — | — | WO | disclosed |