Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBX7 | O95931 | 1/20 | 0.49 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.49 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.49 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | CD74 | P04233 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16932308 | 0.82 | CBX7 (0.50) | CBX7CDYL2CDYLCDY1; CDY1BSIGMAR1 | |
| SCHEMBL30538007 | 0.82 | CBX7 (0.50) | CBX7CDYL2CDYLCDY1; CDY1BSIGMAR1 | |
| SCHEMBL16948384 | 0.82 | KMT2A (0.60) | NPC1CD74MIFKMT2ATSHR | |
| SCHEMBL16932344 | 0.82 | IDO1 (0.64) | KMOIDO1 | |
| SCHEMBL616373 | 0.80 | SIGMAR1 (0.53) | CBX7CDYL2CDYLCDY1; CDY1BSIGMAR1 | |
| SCHEMBL30336433 | 0.80 | SIGMAR1 (0.53) | CBX7CDYL2CDYLCDY1; CDY1BSIGMAR1 | |
| SCHEMBL16939101 | 0.79 | KMO (0.52) | KMOCD74MIFIDO1KMT2A | |
| SCHEMBL20172636 | 0.78 | MIF (0.46) | KMOCD74MIFIDO1KMT2A | |
| SCHEMBL30200079 | 0.78 | MAPK1 (0.66) | MIFIDO1USP2HPGDTSHR | |
| SCHEMBL782891 | 0.77 | SIGMAR1 (0.57) | CBX7CDYL2CDYLCDY1; CDY1BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PREC MEDICINES INC (US) | 2023-07-13 | — | — | US | disclosed |
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PREC MEDICINES INC (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | CBX7 1133/4885CDYL2 1702/4885CDYL 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.