Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.80 |
| ▸ | PARG | Q86W56 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14992536 | 0.86 | GRM2 (0.69) | GRM2PARGSMN1; SMN2 | |
| SCHEMBL624936 | 0.86 | GRM2 (0.66) | GRM2PARGPIK3CD | |
| SCHEMBL625814 | 0.85 | GRM2 (1.00) | GRM2PARG | |
| SCHEMBL10146367 | 0.85 | GRM2 (0.80) | GRM2PARG | |
| SCHEMBL25864985 | 0.85 | GRM2 (0.57) | GRM2PARGPOLBPIK3CDSMN1; SMN2 | |
| SCHEMBL10145959 | 0.85 | GRM2 (0.72) | GRM2PARGPOLB | |
| SCHEMBL10146311 | 0.84 | GRM2 (0.78) | GRM2PARGMAPT | |
| SCHEMBL14992991 | 0.84 | GRM2 (0.78) | GRM2PARG | |
| SCHEMBL10146323 | 0.83 | GRM2 (0.95) | GRM2PARG | |
| SCHEMBL10146324 | 0.83 | GRM2 (0.76) | GRM2PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PREC MEDICINES INC (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219938-A1 | COMPOUNDS AND THEIR METHODS OF USE | SCN1A, SCN3A, SCN1B | GRM2 222/4885PARG 4382/4885POLB 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.