Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18305182 | 0.83 | CYP1A2 (0.38) | ALOX15LMNAHPGDKDM4ECYP3A4 | |
| SCHEMBL29678765 | 0.83 | CYP1A2 (0.38) | ALOX15LMNAHPGDKDM4ECYP3A4 | |
| SCHEMBL9644472 | 0.81 | HPGD (0.47) | ALOX15MAPTLMNAHPGDMAPK1 | |
| SCHEMBL25166188 | 0.81 | L3MBTL1 (0.37) | ALOX15MAPTHPGDALDH1A1GAA | |
| SCHEMBL5987150 | 0.81 | L3MBTL1 (0.38) | ALOX15HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23640216 | 0.78 | MAOB (0.52) | MAPTMAPK1CA1CA2CA12 | |
| SCHEMBL29831530 | 0.77 | KMT2A (0.48) | ALOX15MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL1866136 | 0.77 | KMT2A (0.48) | ALOX15MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL16048103 | 0.75 | KMT2A (0.35) | ALOX15MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL13984211 | 0.74 | ALOX15 (0.53) | ALOX15MAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |