Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25865813 | 0.79 | TGFBR1 (0.45) | CAMKK2TGFBR1PDPK1IKBKEDYRK1A | |
| SCHEMBL25865826 | 0.77 | TGFBR1 (0.44) | CAMKK2TGFBR1PDPK1IKBKEDYRK1A | |
| SCHEMBL25865806 | 0.76 | HTR2A (0.48) | CAMKK2TGFBR1PDPK1IKBKEDYRK1A | |
| SCHEMBL25865803 | 0.76 | HTR2A (0.53) | CAMKK2TGFBR1PDPK1IKBKEDYRK1A | |
| SCHEMBL5618155 | 0.74 | TGFBR1 (0.71) | CAMKK2TGFBR1PDPK1IKBKEDYRK1A | |
| SCHEMBL25865829 | 0.73 | TGFBR1 (0.44) | CAMKK2TGFBR1PDPK1IKBKEDYRK1A | |
| SCHEMBL1050911 | 0.72 | TGFBR1 (0.60) | CAMKK2TGFBR1PDPK1IKBKEDYRK1A | |
| SCHEMBL25866085 | 0.72 | TGFBR1 (0.44) | CAMKK2TGFBR1PDPK1IKBKEDYRK1A | |
| SCHEMBL25865809 | 0.72 | HTR2A (0.46) | CAMKK2TGFBR1PDPK1IKBKEDYRK1A | |
| SCHEMBL25865822 | 0.71 | HTR2A (0.51) | TGFBR1PDPK1IKBKEDYRK1ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141225-A1 | FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS | ONSERO THERAPEUTICS INC. (US) | 2023-07-27 | — | — | WO | disclosed |