Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 5/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26527428 | 0.83 | CTSC (0.46) | CTSCGPR55KCNJ1DDB1CRBN | |
| SCHEMBL24981975 | 0.81 | CTSC (0.56) | CTSCCTSKGPR55KCNJ1KDM1A | |
| SCHEMBL28696393 | 0.81 | CTSC (0.56) | CTSCCTSKGPR55KCNJ1KDM1A | |
| SCHEMBL25865852 | 0.81 | CTSC (0.39) | CTSCCTSKFFAR1FFAR4ASAH1 | |
| SCHEMBL25865853 | 0.77 | CTSC (0.37) | CTSCCTSKKDM1A | |
| SCHEMBL28700457 | 0.76 | CTSC (0.55) | CTSCCTSKGPR55KCNJ1KDM1A | |
| SCHEMBL29455670 | 0.74 | CTSC (0.49) | CTSCCTSKGPR55KCNJ1KDM1A | |
| SCHEMBL32680807 | 0.74 | CTSC (0.49) | CTSCCTSKGPR55KCNJ1KDM1A | |
| SCHEMBL31757849 | 0.73 | CTSC (0.64) | CTSCCTSK | |
| SCHEMBL31758121 | 0.73 | CTSC (0.64) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148308-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2023134656-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | 上海壹典医药科技开发有限公司 | 2023-07-20 | — | — | WO | disclosed |