Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25865847 | 0.83 | CTSC (0.49) | CTSCKCNJ1ASAH1GPR55DDB1 | |
| SCHEMBL18593724 | 0.81 | KCNJ1 (0.45) | CTSCKCNJ1GPR55PKMDDB1 | |
| SCHEMBL16932293 | 0.79 | CTSC (0.52) | CTSCKCNJ1GPR55 | |
| SCHEMBL21985824 | 0.79 | CTSC (0.52) | CTSCKCNJ1GPR55 | |
| SCHEMBL30538029 | 0.79 | CTSC (0.52) | CTSCKCNJ1GPR55 | |
| SCHEMBL30738968 | 0.79 | CTSC (0.52) | CTSCKCNJ1GPR55 | |
| Hydrochloric Acid SCHEMBL30738866 | 0.78 | CTSC (0.51) | CTSCKCNJ1GPR55 | |
| SCHEMBL20172639 | 0.76 | GPR55 (0.46) | KCNJ1GPR55ALDH1A1PKMDDB1 | |
| SCHEMBL21924553 | 0.74 | CTSC (0.66) | CTSC | |
| SCHEMBL16934691 | 0.74 | CTSC (0.66) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148308-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-07-11 | — | — | WO | disclosed |
| EP-4257588-A1 | SMALL MOLECULE INHIBITOR OF CATHEPSIN C AND MEDICINAL USE THEREOF | Reistone Biopharma Company Limited (CN) | 2023-10-11 | — | — | EP | disclosed |