Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 1.00 |
| ▸ | ASAH1 | Q13510 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2590676 | 0.92 | NPSR1 (1.00) | NPSR1ASAH1LMNACASP3POLB | |
| SCHEMBL2590909 | 0.72 | NPSR1 (1.00) | NPSR1ASAH1LMNAKDM4EPOLB | |
| SCHEMBL27312078 | 0.68 | ASAH1 (0.57) | NPSR1ASAH1BCHELMNAKDM4E | |
| SCHEMBL12175482 | 0.67 | NPSR1 (1.00) | NPSR1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL29795580 | 0.66 | ASAH1 (1.00) | NPSR1ASAH1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL2589910 | 0.63 | NPSR1 (0.59) | NPSR1LMNAKDM4ECASP3POLB | |
| SCHEMBL8527698 | 0.62 | NPSR1 (0.45) | NPSR1ASAH1BCHELMNAKDM4E | |
| SCHEMBL8527700 | 0.62 | MEN1 (0.46) | NPSR1ASAH1BCHELMNAKDM4E | |
| SCHEMBL5933236 | 0.61 | ALDH1A1 (0.61) | LMNAPOLBSMN1; SMN2 | |
| SCHEMBL714625 | 0.61 | EPHX1 (0.77) | LMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137220-A1 | SMALL MOLECULE NEUROPEPTIDE S ANTAGONISTS FOR THE TREATMENT OF ADDICTIVE DISORDERS, MOOD, ANXIETY AND SLEEP DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011137220-A1 | SMALL MOLECULE NEUROPEPTIDE S ANTAGONISTS FOR THE TREATMENT OF ADDICTIVE DISORDERS, MOOD, ANXIETY AND SLEEP DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-11-03 | — | — | WO | disclosed |