Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.46 |
| ▸ | HNF4A | P41235 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23558239 | 0.88 | HSD17B1 (0.57) | ESR2MEN1KMT2ACYP1A2APP | |
| SCHEMBL51661 | 0.80 | ALOX5 (0.61) | ALOX5ACMSDHNF4AESR2KDM4E | |
| SCHEMBL29059236 | 0.79 | ALOX5 (0.59) | ALOX5ACMSDHNF4AESR2KDM4E | |
| SCHEMBL27292719 | 0.77 | ALOX5 (0.57) | ALOX5ACMSDHNF4AESR2KDM4E | |
| SCHEMBL4199791 | 0.77 | ALOX5 (0.57) | ALOX5ACMSDHNF4AESR2KDM4E | |
| SCHEMBL3924845 | 0.77 | ALOX5 (0.57) | ALOX5ACMSDHNF4AESR2KDM4E | |
| SCHEMBL11724859 | 0.76 | AKR1B1 (0.59) | ALOX5ACMSDHNF4AKDM4ELMNA | |
| SCHEMBL23558555 | 0.74 | ALOX5 (0.45) | ALOX5ACMSDESR2CYP1A2MCL1 | |
| SCHEMBL8931392 | 0.73 | HSPA5 (0.56) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL5306483 | 0.73 | ALOX5 (0.52) | ALOX5ACMSDHNF4AESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234946-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | ALOX5 977/4885ACMSD 4619/4885HNF4A 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.