Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6286136 | 0.86 | NR4A2 (0.53) | NR4A2CREBBPALOX5SLC22A6PBRM1 | |
| SCHEMBL8131871 | 0.85 | NR4A2 (0.51) | NR4A2CREBBPALOX5SLC22A6PBRM1 | |
| SCHEMBL25139960 | 0.82 | PBRM1 (0.54) | NR4A2CREBBPSLC22A6PBRM1CFTR | |
| SCHEMBL24774358 | 0.80 | TACR1 (0.46) | ALDH1A1SMN1; SMN2MAPTTP53NPSR1 | |
| SCHEMBL3227223 | 0.80 | SPR (0.47) | GPR84KDM4E | |
| SCHEMBL9577474 | 0.79 | PBRM1 (0.47) | NR4A2CREBBPSLC22A6PBRM1CFTR | |
| SCHEMBL25139491 | 0.78 | KDM4E (0.49) | NR4A2CREBBPSLC22A6PBRM1CFTR | |
| SCHEMBL6288439 | 0.76 | KMT2A (0.48) | NR4A2CREBBPALOX5SLC22A6PBRM1 | |
| SCHEMBL17866728 | 0.76 | PBRM1 (0.50) | NR4A2CREBBPSLC22A6PBRM1CFTR | |
| SCHEMBL17866727 | 0.76 | PBRM1 (0.54) | NR4A2CREBBPSLC22A6PBRM1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134608-A1 | FUSED RING COMPOUNDS SERVING AS HPK1 INHIBITORS | 微境生物医药科技(上海)有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-102146081-B | Indoleacetic acid derivatives and preparation method and application thereof | UNIV CAPITAL MEDICAL | 2012-08-22 | — | — | CN | disclosed |
| CN-102146081-A | Indoleacetic acid derivatives and preparation method and application thereof | UNIV CAPITAL MEDICAL | 2011-08-10 | — | — | CN | disclosed |