Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25139960 | 0.83 | PBRM1 (0.54) | PBRM1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL5174863 | 0.82 | PBRM1 (0.49) | PBRM1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL5172407 | 0.82 | PBRM1 (0.49) | PBRM1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL17866728 | 0.80 | PBRM1 (0.50) | PBRM1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL25866775 | 0.79 | NR4A2 (0.54) | PBRM1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL25139491 | 0.79 | KDM4E (0.49) | PBRM1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL6288556 | 0.79 | PBRM1 (0.49) | PBRM1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL1810243 | 0.77 | ALDH1A1 (0.47) | PBRM1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL27411346 | 0.77 | PBRM1 (0.47) | PBRM1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL6205542 | 0.77 | ALDH1A1 (0.47) | PBRM1ALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |