⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3229473 | 0.97 | ADH1A (0.44) | — | |
| Hydrochloric Acid SCHEMBL27925623 | 0.97 | ADH1A (0.44) | — | |
| SCHEMBL389800 | 0.97 | — | — | |
| SCHEMBL16573384 | 0.94 | — | — | |
| SCHEMBL722434 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL4166672 | 0.80 | — | — | |
| Trifluoroacetic Acid SCHEMBL31419183 | 0.78 | ALDH1A1 (0.38) | — | |
| SCHEMBL23072500 | 0.73 | ADH1A (0.50) | — | |
| SCHEMBL24914755 | 0.73 | ADH1A (0.50) | — | |
| SCHEMBL22212617 | 0.73 | ADH1A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646656-B | Pyrimidine hydrazide compounds as PGDS inhibitors | SANOFI AVENTIS SPA | 2013-08-14 | — | — | CN | claimed |
| EP-2597955-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | OncoTherapy Science, Inc. (JP) | 2013-06-05 | — | — | EP | claimed |
| WO-2012016082-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2012-02-02 | — | — | WO | claimed |
| CN-101646656-A | Pyrimidine hydrazide compounds as the PGDS inhibitor | SANOFI AVENTIS FR | 2010-02-10 | — | — | CN | claimed |
| EP-0918052-B1 | Improved polymeric mdi color | BAYER AG (US) | 2003-05-28 | — | — | EP | claimed |
| US-5942151-A | PREVENTING THE DISCOLORATION OF PRODUCING POLYMETHYLENEPOLYPHENYLENE POLYISOCYANATE BY ADDING AN ADDITIVE HYDRAZINE OR A HYDRAZINE DERIVATIVE | BAYER CORPORATION (US) | 1999-08-24 | — | — | US | claimed |
| EP-0918052-A1 | Improved polymeric mdi color | Bayer Corporation (US) | 1999-05-26 | — | — | EP | claimed |
| US-11992811-B2 | Crosslinked hollow-fibre membranes and new process for manufacturing the same | EVONIK OPERATIONS GMBH (DE) | 2024-05-28 | — | — | US | disclosed |
| WO-2023081400-A9 | DIRECTED DEGRON MOLECULES AND APPLICATIONS THEREOF | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023081400-A1 | DIRECTED DEGRON MOLECULES AND APPLICATIONS THEREOF | THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-3959251-A1 | LATENT REACTIVE ADHESIVE PREPARATIONS | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-03-02 | — | — | EP | disclosed |
| US-20210394125-A1 | CROSSLINKED HOLLOW-FIBRE MEMBRANES AND NEW PROCESS FOR MANUFACTURING THE SAME | EVONIK OPERATIONS GMBH (DE) | 2021-12-23 | — | — | US | disclosed |
| EP-3756464-A1 | SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2020-12-30 | — | — | EP | disclosed |
| US-5462960-A | Very good affinity for cannabinoid receptor; having psycho-tropic activity | SANOFI (FR) | 1995-10-31 | — | — | US | disclosed |
| EP-0658546-A1 | Novel 3-pyrazolecarboxamide derivatives with cannabinoid receptor affinity | SANOFI (FR) | 1995-06-21 | — | — | EP | disclosed |
| EP-0328274-A1 | Pt (IV) complexes | JOHNSON MATTHEY, INC., (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0000016-B1 | PROCESS FOR THE PREPARATION OF ALLOPHANATES-SUBSTITUTED POLYISOCYANATES AND THEIR USE IN THE MANUFACTURE OF POLYURETHANE PRODUCTS | BAYER AG (DE) | 1980-07-23 | — | — | EP | disclosed |
| US-4210671-A | Abietamide derivatives, their production and use | ENOMOTO HIROSHI (JP) | 1980-07-01 | — | — | US | disclosed |
| US-4177342-A | FROM CARBAMATE(URETHANE)-CONTAINING ALCOHOLS AND POLYISOCYANATES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |
| EP-0000016-A1 | Process for the preparation of allophanates-substituted polyisocyanates and their use in the manufacture of polyurethane products | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |