Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.70 |
| ▸ | BCHE | P06276 | 6/20 | 0.70 |
| ▸ | ACHE | P22303 | 6/20 | 0.70 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.56 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | PAK4 | O96013 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256526 | 0.92 | APP (0.58) | APPBCHEACHENPY5RRAD52 | |
| SCHEMBL25309780 | 0.87 | APP (0.67) | APPBCHEACHENPY5RCTNNB1 | |
| SCHEMBL25867340 | 0.86 | APP (0.64) | APPBCHEACHENPY5RCTNNB1 | |
| SCHEMBL25867149 | 0.86 | APP (0.66) | APPBCHEACHENPY5RCTNNB1 | |
| SCHEMBL14266651 | 0.85 | APP (0.53) | APPBCHEACHENPY5RNTRK1 | |
| SCHEMBL14256550 | 0.83 | APP (0.61) | APPBCHEACHENPY5RAURKA | |
| SCHEMBL25867456 | 0.83 | APP (0.62) | APPBCHEACHENPY5RCTNNB1 | |
| SCHEMBL30896249 | 0.82 | APP (0.60) | APPBCHEACHENPY5RAURKA | |
| SCHEMBL27224018 | 0.82 | APP (0.60) | APPBCHEACHENPY5RAURKA | |
| SCHEMBL25867223 | 0.82 | APP (0.71) | APPBCHEACHENPY5RCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133221-A2 | SMARCA2/4 INHIBITION AS A STRATEGY TO TREAT TUMORS THAT HARBOR ABERRANT BAF ASSEMBLIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-13 | — | — | WO | disclosed |