Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.71 |
| ▸ | ACHE | P22303 | 7/20 | 0.71 |
| ▸ | USP1 | O94782 | 1/20 | 0.61 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 9/20 | 0.59 |
| ▸ | TCF7L2 | Q9NQB0 | 9/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | UBE2N | P61088 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2588892 | 0.90 | RAD52 (0.74) | BCHEACHEUSP1WDR48RAD52 | |
| SCHEMBL25306105 | 0.84 | APP (0.74) | USP1WDR48RAD52APPKDM4E | |
| SCHEMBL16280669 | 0.84 | ACHE (1.00) | BCHEACHERAD52APPKDM4E | |
| SCHEMBL25309780 | 0.82 | APP (0.67) | BCHEACHEUSP1WDR48CTNNB1 | |
| SCHEMBL4864026 | 0.81 | PDE5A (0.74) | USP1WDR48ALDH1A1LMNAMAPT | |
| SCHEMBL25867149 | 0.81 | APP (0.66) | BCHEACHEUSP1WDR48CTNNB1 | |
| SCHEMBL12176129 | 0.79 | SLC2A1 (0.73) | BCHEACHERAD52APPKDM4E | |
| SCHEMBL12175974 | 0.79 | RAD52 (0.64) | BCHEACHEUSP1WDR48RAD52 | |
| SCHEMBL2256496 | 0.79 | ACHE (0.78) | BCHEACHECTNNB1TCF7L2RAD52 | |
| SCHEMBL3117720 | 0.79 | BCHE (0.78) | BCHEACHEUSP1WDR48CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133221-A2 | SMARCA2/4 INHIBITION AS A STRATEGY TO TREAT TUMORS THAT HARBOR ABERRANT BAF ASSEMBLIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-13 | — | — | WO | disclosed |