Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22781148 | 0.84 | GABRA1 (0.62) | GABRA1GABRB2ELANECTSGHSD17B10 | |
| SCHEMBL1053654 | 0.81 | GABRA1 (0.79) | GABRA1GABRB2TRPA1ELANECTSG | |
| SCHEMBL18330585 | 0.81 | MAPK1 (0.44) | GABRA1GABRB2TRPA1ATMHSD17B10 | |
| SCHEMBL108067 | 0.80 | GABRA1 (0.64) | GABRA1GABRB2ELANECTSGMAPK1 | |
| SCHEMBL28789602 | 0.80 | GABRA1 (0.44) | GABRA1GABRB2TRPA1ATMHSD17B10 | |
| SCHEMBL258656 | 0.79 | GABRA1 (0.63) | GABRA1GABRB2ELANECTSGHSD17B10 | |
| SCHEMBL24581179 | 0.79 | GABRA1 (0.57) | GABRA1GABRB2TRPA1ATMELANE | |
| SCHEMBL1548303 | 0.79 | TRPA1 (0.42) | GABRA1GABRB2TRPA1ATMHSD17B10 | |
| SCHEMBL11677650 | 0.78 | GABRA1 (0.56) | GABRA1GABRB2TRPA1ATMHSD17B10 | |
| SCHEMBL8900885 | 0.78 | TRPA1 (0.50) | GABRA1GABRB2TRPA1ATMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384434-B2 | Reaction of phenols with intermediate triazines | AFTON CHEMICAL CORPORATION (US) | 2008-06-10 | — | — | US | claimed |
| US-20060196111-A1 | Fuel additive composition | AFTON CHEMICAL CORPORATION | 2006-09-07 | — | — | US | claimed |
| US-20060196107-A1 | Cyclic mannich products | AFTON CHEMICAL CORPORATION | 2006-09-07 | — | — | US | claimed |
| EP-1645614-A1 | Preparation of amine derivates from nitriles and phenols | Afton Chemical Corporation (US) | 2006-04-12 | — | — | EP | claimed |
| US-20060059771-A1 | Preparation of amine derivates from nitriles and phenols | AFTON CHEMICAL CORPORATION | 2006-03-23 | — | — | US | claimed |
| US-20050268538-A1 | Reaction of phenols with intermediate triazines | AFTON CHEMICAL CORPORATION | 2005-12-08 | — | — | US | claimed |
| US-20240132791-A1 | FUEL COMPOSITION | AFTON CHEMICAL CORPORATION | 2024-04-25 | — | — | US | disclosed |
| WO-2024068384-A1 | FUEL COMPOSITION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2024-04-04 | — | — | WO | disclosed |
| EP-4345152-A1 | FUEL COMPOSITION | Afton Chemical Corporation (US) | 2024-04-03 | — | — | EP | disclosed |
| CN-117801850-A | Fuel composition | 雅富顿化学公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-3375848-B1 | POLYOL CARRIER FLUIDS AND FUEL COMPOSITIONS INCLUDING POLYOL CARRIER FLUIDS | AFTON CHEMICAL CORP (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-3697873-B1 | METHOD FOR REDUCING LOW SPEED PRE-IGNITION | SHELL INT RESEARCH (NL) | 2021-05-26 | — | — | EP | disclosed |
| CN-110546242-B | Polyol carrier fluid and fuel composition comprising a polyol carrier fluid | 雅富顿化学公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-1749370-A | Preparation of amine derivates from nitriles and phenols | AFTON CHEMICAL CORP (US) | 2006-03-22 | — | — | CN | disclosed |
| US-20050268538-A1 | Reaction of phenols with intermediate triazines | AFTON CHEMICAL CORPORATION | 2005-12-08 | — | — | US | disclosed |
| EP-1602707-A1 | Process for preparing mannich products for uses as fuel additives by reaction of phenols with hexahydro-1,3,5-Triazines | Afton Chemical Corporation (US) | 2005-12-07 | — | — | EP | disclosed |
| EP-1285579-B1 | Bactericidal guanidine derivatives, dermally applicable composition, washing composition, and antibacterial fibre aggregate | AJINOMOTO KK (JP) | 2005-11-02 | — | — | EP | disclosed |
| EP-1285579-A1 | Bactericidal guanidine derivatives, dermally applicable composition, washing composition, and antibacterial fibre aggregate | Ajinomoto Co., Inc. (JP) | 2003-02-26 | — | — | EP | disclosed |
| WO-1997030103-A2 | PREPARATION OF POLYETHERAMINES AND POLYETHERAMINE DERIVATIVES | THE DOW CHEMICAL COMPANY (US) | 1997-08-21 | — | — | WO | disclosed |
| US-5112364-A | Improved valve cleaning | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-12 | — | — | US | disclosed |