Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.51 |
| ▸ | WHR1 | P49842 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MERTK | Q12866 | 5/20 | 0.43 |
| ▸ | GRK6 | P43250 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25867220 | 0.92 | NPY5R (0.53) | NPY5RWHR1KDM4ELMNAGAA | |
| SCHEMBL30455430 | 0.80 | WHR1 (0.62) | NPY5RWHR1KDM4ELMNAGAA | |
| SCHEMBL16280668 | 0.74 | NPY5R (0.62) | NPY5RWHR1KMT2AAPPBCHE | |
| SCHEMBL24649614 | 0.72 | NPY5R (0.79) | NPY5RWHR1KDM4EKMT2AHSD17B10 | |
| SCHEMBL2202771 | 0.71 | NPY5R (0.64) | NPY5RWHR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL14256586 | 0.69 | MERTK (0.49) | NPY5RWHR1KMT2AALDH1A1MERTK | |
| SCHEMBL25309780 | 0.69 | APP (0.67) | NPY5RKDM4ELMNAMAPTKMT2A | |
| SCHEMBL8899277 | 0.68 | NPY5R (1.00) | NPY5RAPPBCHEACHEMERTK | |
| SCHEMBL25867222 | 0.68 | APP (0.70) | NPY5RKDM4ELMNAMAPTKMT2A | |
| SCHEMBL25867149 | 0.68 | APP (0.66) | NPY5RKDM4ELMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133221-A2 | SMARCA2/4 INHIBITION AS A STRATEGY TO TREAT TUMORS THAT HARBOR ABERRANT BAF ASSEMBLIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-13 | — | — | WO | disclosed |