Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | ESRRG | P62508 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25748675 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2AL3MBTL1NAAA | |
| SCHEMBL25964229 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2AL3MBTL1NAAA | |
| SCHEMBL25881309 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1KMT2AL3MBTL1NAAA | |
| SCHEMBL25748766 | 0.86 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2AL3MBTL1NAAA | |
| SCHEMBL25750941 | 0.81 | ESRRG (0.49) | SMN1; SMN2MEN1KMT2AL3MBTL1NAAA | |
| SCHEMBL13778189 | 0.79 | HTT (0.57) | SMN1; SMN2MEN1KMT2AL3MBTL1NAAA | |
| SCHEMBL18563625 | 0.78 | MEN1 (0.59) | SMN1; SMN2MEN1KMT2AL3MBTL1NAAA | |
| SCHEMBL25881500 | 0.77 | L3MBTL1 (0.51) | SMN1; SMN2MEN1KMT2AL3MBTL1NAAA | |
| SCHEMBL16355707 | 0.76 | ESRRG (0.64) | SMN1; SMN2MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL24212715 | 0.75 | PRSS1 (0.42) | SMN1; SMN2L3MBTL1TGM2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212182-A1 | ANTI-TUMOR COMPOUND AND PREPARATION METHOD AND USE THEREOF | DUALITY BIOLOGICS (SUZHOU) CO., LTD. (CN) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212182-A1 | ANTI-TUMOR COMPOUND AND PREPARATION METHOD AND USE THEREOF | RCC2, REN, VHL | SMN1; SMN2 2081/4885MEN1 6/4885KMT2A 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.