SCHEMBL25868518

SCHEMBL25868518

NC(Cc1ccc(-c2cncnn2)cc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPH1 P17752 14/20 0.51
SLC7A5 Q01650 3/20 0.50
HSD17B10 Q99714 2/20 0.49
PTGS1 P23219 3/20 0.49
ALPI P09923 1/20 0.49
PKM P14618 1/20 0.49
XIAP P98170 1/20 0.49
GRB2 P62993 1/20 0.43
ALOX15 P16050 2/20 0.43
HIF1A Q16665 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
EGFR P00533 1/20 0.43
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
HTR2A P28223 1/20 0.43
PTGS2 P35354 1/20 0.43
RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29499922 1.00 TPH1 (0.51) TPH1SLC7A5HSD17B10PTGS1ALPI
SCHEMBL27884073 0.82 TPH1 (0.52) TPH1SLC7A5HSD17B10PTGS1ALPI
SCHEMBL7605461 0.81 SLC7A5 (0.57) TPH1SLC7A5HSD17B10PTGS1ALPI
SCHEMBL7234554 0.81 SLC7A5 (0.57) TPH1SLC7A5HSD17B10PTGS1ALPI
SCHEMBL15661160 0.80 SLC7A5 (0.56) TPH1SLC7A5HSD17B10PTGS1ALPI
SCHEMBL15662401 0.80 SLC7A5 (0.56) TPH1SLC7A5HSD17B10PTGS1ALPI
SCHEMBL31370434 0.79 CYP1A2 (0.60) TPH1SLC7A5HSD17B10PTGS1ALPI
SCHEMBL7615000 0.79 TPH1 (0.55) TPH1SLC7A5HSD17B10PTGS1ALPI
SCHEMBL25868356 0.79 CYP1A2 (0.60) TPH1SLC7A5HSD17B10PTGS1ALPI
SCHEMBL7615005 0.79 TPH1 (0.55) TPH1SLC7A5HSD17B10PTGS1ALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4282876-A1 URICASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF Proabtech Inc. (KR) 2023-11-29 EP disclosed
US-20230211002-A1 URATE OXIDASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREOF, AND USE THEREOF PROABTECH CO., LTD. (KR) 2023-07-06 US disclosed
US-20230149517-A1 URATE OXIDASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREOF, AND USE THEREOF PROABTECH CO., LTD. (KR) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149517-A1 URATE OXIDASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREOF, AND USE THEREOF ALB, AOX1, PNPO TPH1 3122/4885SLC7A5 3194/4885HSD17B10 867/4885
US-20230211002-A1 URATE OXIDASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREOF, AND USE THEREOF ALB, AOX1, PNPO TPH1 3122/4885SLC7A5 3194/4885HSD17B10 867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.