Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTM2 | P28161 | 9/20 | 0.51 |
| ▸ | GSTP1 | P09211 | 8/20 | 0.51 |
| ▸ | IDO1 | P14902 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.46 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089701 | 0.84 | GSTM2 (0.56) | GSTM2GSTP1IDO1MEN1KMT2A | |
| SCHEMBL28945749 | 0.82 | GSTM2 (0.46) | GSTM2GSTP1IDO1MEN1KMT2A | |
| SCHEMBL28945752 | 0.82 | GSTM2 (0.43) | GSTM2GSTP1IDO1MEN1KMT2A | |
| SCHEMBL7052057 | 0.80 | GSTM2 (0.66) | GSTM2GSTP1IDO1MEN1KMT2A | |
| SCHEMBL8788825 | 0.80 | GSTM2 (0.51) | GSTM2GSTP1IDO1MEN1KMT2A | |
| SCHEMBL17571734 | 0.78 | GSTP1 (0.42) | GSTM2GSTP1IDO1MEN1KMT2A | |
| SCHEMBL25866704 | 0.77 | GABRA1 (0.34) | MEN1KMT2AUSP2HPGDHSD17B10 | |
| SCHEMBL18056297 | 0.76 | GSTP1 (0.55) | GSTM2GSTP1IDO1MEN1KMT2A | |
| SCHEMBL2608494 | 0.75 | GSTP1 (0.61) | GSTM2GSTP1IDO1MEN1KMT2A | |
| SCHEMBL12337785 | 0.73 | IDO1 (0.60) | GSTM2GSTP1IDO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | UNIV YALE (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | ASGR1, LDLR, FCGR2A | GSTM2 442/4885GSTP1 818/4885IDO1 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.