Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1925518 | 0.87 | GPR84 (0.37) | CCNE1CDK2MAPTALOX5GPR84 | |
| SCHEMBL3328605 | 0.84 | ALOX5 (0.37) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL21821559 | 0.83 | CCNE1 (0.36) | CCNE1CDK2TYRCYP3A4ALOX15 | |
| SCHEMBL9418551 | 0.83 | CCNE1 (0.36) | CCNE1CDK2TYRCYP3A4ALOX15 | |
| SCHEMBL3284127 | 0.83 | CCNE1 (0.36) | CCNE1CDK2TYRCYP3A4ALOX15 | |
| SCHEMBL1271005 | 0.81 | CCNE1 (0.44) | CCNE1CDK2CYP3A4MAPTTP53 | |
| SCHEMBL10015711 | 0.77 | SMN1; SMN2 (0.38) | CCNE1CDK2MAPTMEN1TSHR | |
| SCHEMBL2211671 | 0.77 | GPR84 (0.39) | CCNE1CDK2MAPTMEN1TP53 | |
| SCHEMBL21708438 | 0.76 | SMN1; SMN2 (0.36) | CCNE1CDK2MAPTMEN1TSHR | |
| SCHEMBL20533612 | 0.75 | PTGS1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632983-A1 | THERMOPLASTIC GEL SEALANTS | Tyco Electronics Corporation (US) | 2013-09-04 | — | — | EP | disclosed |
| EP-2629615-A1 | SLOW-RELEASE FORMULATIONS OF 5-HYDROXYTRYPTOPHAN AS AN ADJUNCT TO PRO-SEROTONERGIC THERAPIES | Duke University (US) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012058087-A1 | THERMOPLASTIC GEL SEALANTS | TYCO ELECTRONICS CORPORATION (US) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012054815-A1 | SLOW-RELEASE FORMULATIONS OF 5-HYDROXYTRYPTOPHAN AS AN ADJUNCT TO PRO-SEROTONERGIC THERAPIES | DUKE UNIVERSITY (US) | 2012-04-26 | — | — | WO | disclosed |
| CN-102356123-A | Flame-retardant expandable styrene resin composition | DAI ICHI KOGYO SEIYAKU CO LTD | 2012-02-15 | — | — | CN | disclosed |
| WO-2011137321-A1 | THICKENED COMPOSITONS OF HIGH PH | ISP INVESTMENTS INC. (US) | 2011-11-03 | — | — | WO | disclosed |
| EP-1713486-A4 | COMBINATION THERAPY FOR DEMENTIA,DEPRESSION AND APATHY | SHELDON LESLIE JAMES (CA) | 2009-04-29 | — | — | EP | disclosed |
| EP-1746985-A2 | METHOD FOR AUGMENTING THE EFFECTS OF SEROTONIN REUPTAKE INHIBITORS | DUKE UNIVERSITY (US) | 2007-01-31 | — | — | EP | disclosed |
| EP-1713486-A1 | COMBINATION THERAPY FOR DEMENTIA,DEPRESSION AND APATHY | Sheldon, Leslie James (CA) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005112906-A2 | METHOD FOR AUGMENTING THE EFFECTS OF SEROTONIN REUPTAKE INHIBITORS | DUKE UNIVERSITY (US) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005053703-A1 | COMBINATION THERAPY FOR DEMENTIA, DEPRESSION AND APATHY | SHELDON LESLIE JAMES (CA) | 2005-06-16 | — | — | WO | disclosed |