SCHEMBL25868750

SCHEMBL25868750

COc1cn(S(=O)(=O)n2cnc(OC)c2)cn1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
KDM4E B2RXH2 1/20 0.36
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PKM P14618 2/20 0.35
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.32
GAA P10253 1/20 0.32
AMY1A P0DUB6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27819609 0.84 MAPT (0.38) MAPTKDM4ELMNASMN1; SMN2PKM
SCHEMBL25836668 0.81 HTT (0.42) MAPTKDM4ELMNASMN1; SMN2PKM
SCHEMBL2515860 0.69
SCHEMBL6275526 0.65 SIRT6 (0.35) KDM4ELMNASMN1; SMN2ALDH1A1KMT2A
SCHEMBL25237385 0.64
SCHEMBL22143336 0.64 CDK5 (0.39)
SCHEMBL22168314 0.64
SCHEMBL21720047 0.64
SCHEMBL4045244 0.56 HTT (0.44) KDM4ELMNASMN1; SMN2TSHRGAA
SCHEMBL28610470 0.55 SIRT6 (0.46) LMNASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134691-A1 HIGH-VOLTAGE ELECTROLYTE AND BATTERY CONTAINING ELECTROLYTE 珠海冠宇电池股份有限公司 2023-07-20 WO disclosed